Linear quadratic model : D2 = D1(α/β + d1) / (α/β + d2)
Several factors should be considered before using the Linear Quadratic Model :  Dose / fraction : must be between 1 and 6 Gy. The linear quadratic model should not be used for hypofractionated regimen.  Time between fractions : Two treatment sessions should not be performed with less than 6 to 8 hours between them. The Linear Quadratic Model should not be used for accelerated treatments.

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